Projects
View
| Name | IDEA-FAST |
|---|---|
| Long Name | Identifying digital endpoints to assess fatigue, sleep and activities in daily living in neurodegenerative disorders and immune-mediated inflammatory diseases |
| Description | Identifying digital endpoints to assess fatigue, sleep and activities in daily living in neurodegenerative disorders and immune-mediated inflammatory diseases. IDEA-FAST aims to identify digital endpoints that provide reliable, objective and sensitive evaluation of activities of daily life (ADL), disability and health related-quality of life (HRQoL) for the following neurodegenrative diseases (NDD): Parkinson’s Disease (PD), Huntington’s Disease (HD) and the following immune-mediated inflammatory diseases (IMID): Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE), Primary Sjögren’s Syndrome (PSS), and Inflammatory Bowel Disease (IBD). |
| Objectives | 1. Select a set of digital endpoints and corresponding digital devices/technologies for the evaluation of fatigue and sleep disturbances for clinical validation, and to explore digital correlates of other ADLs by profiling activity, biological, neurocognitive and behavioural aspects in patients with IBD, RA, SLE, PSS, PD and HD. 2. Implement a robust, seamless, interoperable and secure digital management platform that is compliant with legal and data privacy requirements to support data acquisition, storage, analysis of patient and professional information; and to define standards for data integration, analysis, storage and sharing (including secondary use of data to maximise impact and exploitation). 3. Establish a large and well-characterised longitudinal cohort of IBD, RA, SLE, PSS, PD and HD patients with detailed records about the candidate digital endpoints described in objective 1. 4. Evaluate the clinical validity of the candidate digital endpoints compared to gold standards, and to seek qualification advice of their use as novel digital endpoints by regulatory agencies such as EMA, and to obtain opinion about the role of these endpoints in supporting health utility evaluation by Health Technology Agencies (HTA). 5. Ensure a lasting impact through the creation of a properly annotated database compatible with the International Classification of Functioning, Disability, and Health (ICF) which will include real-world digital datasets of biophysiological, neurocognitive, behavioural, personal, environmental and socialization observations coupled with comprehensive clinical data to support the possible finalization of the regulatory qualification process to foster future academic and industrial studies aimed to develop novel treatments. |
| Website | https://ideafast.eu/ |
| Start date | 01-11-2019 |
| End date | 30-04-2025 |
| Logo |  |
| Name | Projects | Type of institution | Country | |
|---|---|---|---|---|
| Abbvie Inc. | EQIPD IDEA-FAST | EFPIA | United States | |
| Astrazeneca AB | MOPEAD PHAGO Mobilise-D IDEA-FAST PD-MIND Pharma-Cog | EFPIA | Sweden | |
| Biogen Idec Limited | EPAD RADAR-CNS ROADMAP ADAPTED IDEA-FAST | EFPIA | United Kingdom | |
| Eli Lilly And Company Ltd | EPAD IMPRiND MOPEAD PHAGO PRISM RADAR-AD ROADMAP NEURONET IDEA-FAST Pharma-Cog | EFPIA | United Kingdom | |
| F. Hoffmann-La Roche AG | EPAD EQIPD EMIF PHAGO PRISM ROADMAP NEURONET IDEA-FAST Pharma-Cog EPND | EFPIA | Switzerland | |
| Janssen Pharmaceutica NV | EPAD ADAPTED AMYPAD IMPRiND EQIPD NEURONET EMIF IM2PACT PHAGO PRISM RADAR-CNS RADAR-AD ROADMAP IDEA-FAST Pharma-Cog EPND | EFPIA | Belgium | |
| Orion Oyj | EQIPD PHAGO IDEA-FAST | EFPIA | Finland | |
| Pfizer Limited | EPAD EQIPD EMIF IM2PACT PRISM Mobilise-D IDEA-FAST | EFPIA | United Kingdom | |
| Sanofi-Aventis Recherche & Developpement | EPAD EQIPD AETIONOMY IM2PACT PHAGO NEURONET Mobilise-D IDEA-FAST EPND | EFPIA | France | |
| UCB Biopharma SPRL | EPAD EQIPD AETIONOMY EMIF PD-MitoQUANT RADAR-CNS IDEA-FAST Pharma-Cog EPND | EFPIA | Belgium | |
| Academisch Ziekenhuis Leiden | PRISM IM2PACT ROADMAP IDEA-FAST PRISM2 | Academia | Netherlands | |
| Ecrin European Clinical Research Infrastructure Network | IDEA-FAST | Academia | France | |
| Erasmus Universitair Medisch Centrum Rotterdam | PRISM ADAPTED AETIONOMY EMIF ROADMAP EPAD IDEA-FAST | Academia | Netherlands | |
| Fciencias.Id - Associacao Para A Investigacao E Desenvolvimento De Ciencias | IDEA-FAST | Academia | Portugal | |
| Helse Stavanger Hf | IDEA-FAST PD-MIND | Academia | Norway | |
| Imperial College Of Science Technology And Medicine | EQIPD Mobilise-D IDEA-FAST | Academia | United Kingdom | |
| Institut Mines-Telecom | IDEA-FAST | Academia | France | |
| Instituto De Medicina Molecular Joao Lobo Antunes | IDEA-FAST | Academia | Portugal | |
| Instytut Psychiatrii I Neurologii | IDEA-FAST | Academia | Poland | |
| Medizinische Universitat Innsbruck | IDEA-FAST | Academia | Austria | |
| Queen Mary University Of London | IDEA-FAST | Academia | United Kingdom | |
| Teknologian Tutkimuskeskus VTT Oy | EMIF IDEA-FAST | Academia | Finland | |
| The University Of Manchester | IDEA-FAST | Academia | United Kingdom | |
| Tmf - Technologie Und Methodenplattform Fur Die Vernetzte Medizinische Forschung Ev | IDEA-FAST | Academia | Germany | |
| Universidad Autonoma de Madrid | IDEA-FAST | Academia | Spain | |
| Universita Degli Studi Di Brescia | IDEA-FAST | Academia | Italy | |
| Universitätsklinikum Schleswig-Holstein | EMIF IDEA-FAST | Academia | Germany | |
| University Of Glasgow | EMIF IDEA-FAST | Academia | United Kingdom | |
| University Of Limerick | IDEA-FAST | Academia | Ireland | |
| University Of Newcastle Upon Tyne | Mobilise-D IDEA-FAST | Academia | United Kingdom | |
| University Of Cambridge | EPAD IMPRiND PHAGO EMIF IDEA-FAST | Academia | United Kingdom | |
| Byteflies | IDEA-FAST | SME | Belgium | |
| Cambridge Cognition Ltd | EMIF IDEA-FAST | SME | United Kingdom | |
| Dreem | IDEA-FAST | SME | France | |
| Empirica Gesellschaft Fur Kommunikations Und Technologieforschung Mbh | IDEA-FAST | SME | Germany | |
| George-Huntington-Institut GMBH | IDEA-FAST | SME | Germany | |
| Ixscient Limited, Uxbridge | Mobilise-D IDEA-FAST | SME | United Kingdom | |
| Lixoft SAS | IDEA-FAST | SME | France | |
| McRoberts BV | Mobilise-D IDEA-FAST | SME | Netherlands | |
| Medibiosense LTD | IDEA-FAST | SME | United Kingdom | |
| Pluribus One SRL | IDEA-FAST | SME | Italy | |
| Stichting Mlc Foundation | IDEA-FAST | SME | Netherlands | |
| Asociacion Parkinson Madrid | IDEA-FAST | Patient/carers organisation | Spain | |
| European Federation Of Crohn's And Ulcerative Colitis Associations | IDEA-FAST | Patient/carers organisation | Belgium | |
| Parkinson's Disease Society Of The United Kingdom LBG | NEURONET PD-MitoQUANT IDEA-FAST PD-MIND | Patient/carers organisation | United Kingdom | |
| Christian-Albrechts-Universitaet Zu Kiel | Mobilise-D IDEA-FAST | Academia | Germany | |
| Faculdade De Ciencias Da Universidade De Lisboa | IDEA-FAST | Academia | Portugal | |
| Greater Glasgow Health Board | IDEA-FAST | Academia | United Kingdom | |
| Kks-Netzwerk Ev -Netzwerk Der Koordinierungszentren Fur Klinische Studien | IDEA-FAST | Academia | Germany | |
| CHDI Foundation, Inc. | IDEA-FAST | Academia | United States | |
| Takeda Pharmaceuticals International AG | EPND EPAD PRISM RADAR-AD ROADMAP IDEA-FAST Mobilise-D NEURONET | EFPIA | Switzerland |
| WP number | Description | Project | |
|---|---|---|---|
| WP1 | Project Management and Oversight | IDEA-FAST | |
| WP2 | Clinical Knowledge and Insight | IDEA-FAST | |
| WP3 | Digital Device and Technology | IDEA-FAST | |
| WP4 | Device-specific Data Analytics and Performance Assessment | IDEA-FAST | |
| WP5 | Data Management | IDEA-FAST | |
| WP6 | Clinical Study Organisation & Management | IDEA-FAST | |
| WP7 | Statistical Inference Design and Learning | IDEA-FAST | |
| WP8 | Data Protection, Ethics and Legal Challenges | IDEA-FAST | |
| WP9 | Dissemination, Exploitation & Sustainability | IDEA-FAST |
| Deliverable number | Title | Project | Submission date | Link | Keywords | |
|---|---|---|---|---|---|---|
| D1.1 | Project Handbook | IDEA-FAST | 27-03-2020 | https://idea-fast.eu/wp-content/uploads/2020/10/IDEA-FAST_D1.1_Project-Handbook_v1.0-IMI.pdf | ||
| D1.2 | Risk assessment process and management procedure | IDEA-FAST | 21-10-2020 | https://idea-fast.eu/wp-content/uploads/2020/10/IDEA-FAST_D1.2_Risk-Assessment_v1.0.pdf | ||
| D2.1 | First study subject approvals package of the Feasibility Study (FS) | IDEA-FAST | 31-07-2020 | https://idea-fast.eu/wp-content/uploads/2020/10/IDEA-FAST_D2.1_FS-Approvals_v1.0_IMI.pdf | ||
| D3.1 | Device Selection Criteria and Documents / Processes for Gathering Evidence | IDEA-FAST | 31-03-2020 | https://idea-fast.eu/wp-content/uploads/2020/10/IDEA-FAST_D3.1_DeviceSelectionCriteriaAndDocuments_v1.pdf | ||
| D5.1 | Data Management Plan | IDEA-FAST | 31-03-2020 | https://idea-fast.eu/wp-content/uploads/2020/10/D5.1-IDEA-FAST_DMP_v10.pdf | ||
| D8.2 | The model informed consent for the FS | IDEA-FAST | 31-03-2020 | https://idea-fast.eu/wp-content/uploads/2022/01/IDEA-FAST_D8.2-Model-Informed-Consent-for-the-CVS_V1.0.pdf | ||
| D9.1 | Detailed Dissemination Plan | IDEA-FAST | 29-05-2020 | https://idea-fast.eu/wp-content/uploads/2020/10/D9.1-Dissemination-Plan-V1.0.pdf | ||
| D5.2 | Specification of IDEA-FAST DMP | IDEA-FAST | 30-10-2020 | https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5d54ee72b&appId=PPGMS | ||
| D4.1 | Definition of assessment protocol for device-specific digital endpoints | IDEA-FAST | 06-10-2020 | https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5d459bc85&appId=PPGMS | ||
| D2.4 | Mid-term recruitment report of the feasibility study (FS) | IDEA-FAST | 05-01-2021 | https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5d7b421aa&appId=PPGMS | ||
| D5.4 | Public version of IDEA-FAST clinical and sensor data standards | IDEA-FAST | 08-12-2021 | https://idea-fast.eu/wp-content/uploads/2022/01/IDEA-FAST_D5.4_Data_Standards_V1.0.pdf | ||
| D6.1 | First version of the CVS protocol | IDEA-FAST | 18-10-2021 | https://idea-fast.eu/wp-content/uploads/2022/01/IDEA-FAST_D6.1_CVS-Protocol_V1.0_IMI.pdf | ||
| D8.1 | The model informed consent for the FS | IDEA-FAST | 31-03-2020 | https://idea-fast.eu/wp-content/uploads/2021/01/IDEA-FAST_D8.1-Model-Informed-Consent-for-the-FS-V1.pdf | ||
| D4.4 | Requirements specification data analytics software package | IDEA-FAST | 31-12-2021 | https://idea-fast.eu/wp-content/uploads/2022/04/IDEA-FAST_D4.4_RequirementsSpecificationDataAnalyticsSW_V1.0.pdf | ||
| D6.2 | Finalised master documents in English for ethical/regulatory submissions, including study protocol & PIS/ICF for the COS | IDEA-FAST | 09-05-2022 | https://idea-fast.eu/wp-content/uploads/IDEA-FAST_D6.2_Finalised-Master-Documents_V1.0_IMI.pdf | ||
| D9.2 | Definitions of the exploitation and socio- economic evaluation framework | IDEA-FAST | 13-05-2022 | https://idea-fast.eu/wp-content/uploads/IDEA-FAST_D9.2_Exploitationsocio-economic-evaluation-framework_V1.0.pdf | ||
| D2.4 | Report factors identified by historical data of published data | IDEA-FAST | 25-11-2021 | https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5e17bd000&appId=PPGMS |
| Title | First author last name | Year | Project | Link | Keywords | |
|---|---|---|---|---|---|---|
| Making Sense of Sleep: Multimodal Sleep Stage Classification in a Large, Diverse Population Using Movement and Cardiac Sensing | Zhai | 2020 | IDEA-FAST | https://doi.org/10.1145/3397325 | ||
| Data Contribution Summaries for Patient Engagement in Multi-Device Health Monitoring Research | Rainey | 2021 | IDEA-FAST | https://doi.org/10.1145/3460418.3479371 | digital health, human-centered design, in-the-wild studies, wearables, sensing devices, patient engagement, human-data interaction | |
| A blockchain-based trust system for decentralised applications: When trustless needs trust | Truong | 2021 | IDEA-FAST | https://doi.org/10.1016/j.future.2021.05.025 | Blockchain, DApps, Decentralised ecosystem, Reputation, Trust system | |
| Privacy preservation in federated learning: An insightful survey from the GDPR perspective | Truong | 2021 | IDEA-FAST | https://doi.org/10.1016/j.cose.2021.102402 | Federated learning, Data protection regulation, GDPR, Personal data, Privacy, Privacy preservation | |
| Symbolic AI for XAI: Evaluating LFIT Inductive Programming for Explaining Biases in Machine Learning | Ortega | 2021 | IDEA-FAST | https://doi.org/10.3390/computers10110154 | explainable artificial intelligence; inductive logic programming; fair recruitment; fair income level; propositional logic |
| Title | Description | Type | Project | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No entries in table | ||||||||||
| Website: https://ideafast.eu/ |
Back to list