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Name EPND
Long Name European Platform for Neurodegenerative Diseases
Description The European Platform for Neurodegenerative Diseases (EPND) integrates existing initiatives to build, grow, and deliver a scalable and self-sustainable platform for storage and analysis of high-quality clinical samples and data collections. It is a public-private partnership funded by the Innovative Medicines Initiative (IMI), aiming to become a future European infrastructure, facilitating access to biological samples and data to accelerate biomarker discovery and validation and eventually support the development of therapeutics for neurodegenerative diseases.
Objectives 1. Create a set of agreed ethical, legal, regulatory, business and sustainability principles to establish governance and operational processes to enable sharing and access to data and samples; 2. Establish a network that provides central and federated access to high quality samples and data from over 60 cohorts by combining existing data discovery and sharing initiatives made interoperable as part of the AD Workbench. In addition to enabling the sharing and access of data and samples, the platform will provide central and federated capabilities to ensure unified interpretation of biomarker data.; 3. Provide visibility into the quality and standardization of the data and samples available in the platform from existing cohorts. Similarly, for prospective cohorts the development of SOPs will guarantee the quality of samples and data available, which will be important when focusing on the regulatory approval path for biomarkers; 4. Perform a robust evaluation of the developing EPND platform through the execution of case studies on the Amyloid-Tau-Neurodegeneration (ATN) staging, complement activation, microbiome markers and molecular subtypes; 5. Embrace sustainability from the start of the project by designing and piloting exploitation strategies such that the platform is self-sustainable by the end of the project.
Website https://epnd.org/
Start date 01-11-2021
End date 31-10-2026
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Name Projects Type of institution Country  
F. Hoffmann-La Roche AG EPAD EQIPD EMIF PHAGO PRISM ROADMAP NEURONET IDEA-FAST Pharma-Cog EPND EFPIA Switzerland
Ac Immune SA EPAD ROADMAP EPND EFPIA Switzerland
Gates Ventures Llc EPND Other United States
Janssen Pharmaceutica NV EPAD ADAPTED AMYPAD IMPRiND EQIPD NEURONET EMIF IM2PACT PHAGO PRISM RADAR-CNS RADAR-AD ROADMAP IDEA-FAST Pharma-Cog EPND EFPIA Belgium
Novartis Pharma AG EPAD IMPRiND EQIPD AETIONOMY IM2PACT PRISM RADAR-AD ROADMAP Mobilise-D Pharma-Cog EPND EFPIA Switzerland
S.A. Life Science AB EPND EFPIA Sweden
Sanofi-Aventis Recherche & Developpement EPAD EQIPD AETIONOMY IM2PACT PHAGO NEURONET Mobilise-D IDEA-FAST EPND EFPIA France
Takeda Pharmaceuticals International AG EPND EPAD PRISM RADAR-AD ROADMAP IDEA-FAST Mobilise-D NEURONET EFPIA Switzerland
Teva Pharmaceutical Industries Limited PD-MitoQUANT Mobilise-D EQIPD EPND EFPIA Israel
UCB Biopharma SPRL EPAD EQIPD AETIONOMY EMIF PD-MitoQUANT RADAR-CNS IDEA-FAST Pharma-Cog EPND EFPIA Belgium
Academisch Ziekenhuis Groningen EPND Academia Netherlands
Agentschap College Ter Beoordeling Van Geneesmiddelen RADAR-AD ROADMAP EPND Academia Netherlands
Biobanks And Biomolecular Resources Research Infrastructure Consortium (Bbmri-Eric) EPND Academia Australia
Centre Hospitalier Universitaire Vaudois EPND Academia Switzerland
Deutsches Zentrum Fur Neurodegenerative Erkrankungen Ev IMPRiND PD-MitoQUANT PHAGO EPND Academia Germany
Eatris Eric EPND Academia Netherlands
Goeteborgs Universitet PHAGO ROADMAP EMIF EPND Academia Sweden
King's College London PHAGO RADAR-CNS RADAR-AD EMIF PD-MIND EPND Academia United Kingdom
Luxembourg Institute Of Health EPND Academia Luxembourg
Alzheimer Europe EPAD AMYPAD MOPEAD AETIONOMY EMIF RADAR-AD ROADMAP NEURONET Pharma-Cog EPND Patient/carers organisation Luxembourg
VU University Medical Center Amsterdam EPAD AMYPAD IM2PACT PRISM MOPEAD RADAR-CNS RADAR-AD EMIF PRISM2 Pharma-Cog EPND Academia Netherlands
Universite De Geneve EPAD AMYPAD EPND Academia Switzerland
Université du Luxembourg AETIONOMY EPND Academia Luxembourg
Universiteit Maastricht ROADMAP EMIF EPND Academia Netherlands
University Of Leicester EPAD EMIF EPND Academia United Kingdom
University Of Oxford EPAD IMPRiND IM2PACT RADAR-AD ROADMAP EMIF EPND Academia United Kingdom
Aridhia Informatics Ltd EPAD EPND SME United Kingdom
Lygature RADAR-CNS RADAR-AD PD-MIND EPND SME Netherlands
Bmd Software Lda EPND SME Portugal
WP number Description Project  
WP1 Establishment of the platform EPND
WP2 WP2 Legal and ethical aspects EPND
WP3 SOP Development EPND
WP4 Cohort Interaction EPND
WP5 Case Studies EPND
WP6 Stakeholder involvement, external communication and dissemination EPND
WP7 Sustainability and exploitation of the platform EPND
WP8 Management and overall coordination EPND
Deliverable number Title Project Submission date Link Keywords  
No entries in table
Title First author last name Year Project Link Keywords  
Data and sample sharing as an enabler for large-scale biomarker research and development: The EPND perspective Bose 2022 EPND https://doi.org/10.3389/fneur.2022.1031091 neurodegenerative disease, Alzheimer's disease, data-sharing, sample-sharing, platforms, biomarker research, cohort
Title Description Type Project  
No entries in table
Website: https://epnd.org/

 

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